About Dr. Joseph Gretzula, D.O., F.A.A.D.

EDUCATIONAL BACKGROUND AND PHILOSOPHY

Dr. Joseph C. Gretzula is a Board-Certified Dermatologist who has served South Florida for over 31 years. He
received his training in Dermatology at the world-renowned Dr. Phillip Frost Department of Dermatology and
Cutaneous Surgery at the University of Miami. He is Board-Certified in Dermatology and is a Diplomat of the
American Board of Dermatology. He is also a Fellow of the American Academy of Dermatology, the American
Society of Dermatologic Surgery, the Florida Society of Dermatology and Dermatologic Surgery, and a member of
the Florida Society of Dermatologic Surgery. Dr. Gretzula is presently on the Voluntary Faculty at the University of
Miami Department of Dermatology and Cutaneous Surgery and locally serves on staff at Bethesda Memorial
Hospital located in Boynton Beach, FL. Dr. Gretzula specializes in both the diagnosis and treatment of Skin
Cancers, which has reached epidemic proportions worldwide and especially here in South Florida.

Dr. Gretzula also holds a Bachelor of Science (BS) Degree in Pharmacy, having trained at the Philadelphia College
of Pharmacy and Science, the first School of Pharmacy in North America. Throughout his training in Pharmacy, he
procured a unique understanding and love of Pharmacology and the Science of Pharmacognosy. Pharmacognosy
is a branch of Pharmacy that deals specifically with the study of medicinal and/or pharmaceutical substances
derived from natural sources including plants, fungi, and animals. Throughout his daily interactions with his
patients, Dr. Gretzula routinely advises patients regarding potential drug interactions as well as provides advice on
oral vitamin supplementation and herbal medicinal agents.

Having trained as both an Osteopathic and Allopathic physician and a Pharmacologist, Dr. Gretzula has
incorporated a more holistic approach to the Practice of Dermatology. His other passions include Art, Science, and
Nutrition. There are tremendous parallels between Art and Science, as each reflects and incorporates creativity
and the curiosity for the unknown. They both reflect on a very simple premise “to explore and reflect an interest
in creating something new”.

Dr. Gretzula recently incorporated Precision Medicine into his practice. Gone are the days of one size fits all
patient care. A more personal approach, one specifically tailored to a person’s needs, should be the focus of
today’s medical practices. Precision Medicine has gained tremendous traction, thanks to better access to genome
sequencing and a constant stream of studies demonstrating that gene variance affects skin disease and its
treatment. Precision Nutrition takes a similar approach and aims to prevent disease through proper nutrition. The
concept of Precision Nutrition is that the interaction between a person’s genotype and their nutritional intake,
behavioral lifestyle, and socioeconomic environment together influences overall health. Leading experts refer to
this intricate interplay as “Nutrition Phenotype”, and they believe that this refined approach to nutrition will
change clinical care. There has been increasing recognition that an individual’s diet and environment may impact
disease susceptibility by affecting the expression of genes involved in clinical metabolic pathways.

Each and every day there are innumerable articles delineating the importance of our gut bacteria (Microbiome)
and its relationship to the skin including its effects on common dermatologic conditions such as Acne Vulgaris,
Acne Rosacea, and Atopic Dermatitis, as well as Chronological and Photoaging. It has also been well documented
that our gut bacteria play an important role in achieving a better skin complexion. Recent studies have also
confirmed that our gut bacteria are part of an integrated system that affects all of our body including the brain
and the immune system. Each of us possess our own Microbiome of gastrointestinal organisms which affect our
immune system, metabolism, stress, and inflammation throughout our body including our brain. Recent studies
have also indicated a direct relationship between our Microbiome and Depression, Autism, ADHD, Parkinson’s
Disease and many other neurological conditions including Alzheimer’s Disease. Therefore, altering our gut
bacteria through supplementation of oral probiotics and prebiotics, as well as adapting changes in our diet
incorporating intermittent fasting, may have a major effect in improving our skin health as well as our total
wellbeing. Recent studies have also shown that intermittent fasting, itself, may even cure Type-2 Diabetes and
may prevent individuals with Prediabetes from developing full blown Diabetes.

Dr. Gretzula welcomes you to share in his passion of incorporating Precision Medicine and Nutrition through
studying one’s genotype, gut bacteria, environmental and lifestyle changes, as well as disease risks in creating a
healthy living environment and a more active viable life as we age.

PERSONAL DATA:

Date of Birth: January 28, 1957
Place of Birth: Scranton, Pennsylvania, U.S.A.

EDUCATION AND TRAINING

Post-Graduate:
University of Miami School of Medicine
Jackson Memorial Hospital, Miami, FL – 1984-87
Residency: Dermatology
1984: Resident of the Year, Jackson Memorial Hospital

Geisinger Medical Center
Danville, PA – 1983-84
Internship: Internal Medicine
Completed all internship rotations with an “A”

Graduate:
Philadelphia College of Osteopathic Medicine
Philadelphia, PA – 1979-83
Degree: Doctor of Osteopathy, D.O.
1983: Honor Student-Class Rank 1st in 203
1982: William Goldman Foundation Award
1980: Christian & Mary Lindback Fdn. Award

Undergraduate:
Philadelphia College of Pharmacy & Science
Philadelphia, PA – 1975-79
Degree: B.S. Pharmacy, Magna Cum Laude
1979: Honor Student-Class Rank 2nd in 219
1979: Merck, Sharp & Dome Award
1978: Joseph W. Harrison Award
1977: Rho Chi Society – Pharmaceutical Honor Society
1976: Woodside Memorial Scholarship
Member: Alumni Association, PCPS

Keystone Jr. College, La Plume, PA – 1974-75
Major: Pre-Pharmacy
Dean’s List/Honor Student

LICENSURE
Florida D.O. #0S5031
Montana MED-PHYS – LIC-11236
Pennsylvania D.O. – Inactive
New Jersey Flex – Inactive
Pennsylvania RP – 030631 – L

HOSPITAL AFFILIATIONS
Bethesda Memorial Hospital, Boynton Beach, Florida

FACULTY APPOINTMENTS (Voluntary Faculty)
Palm Beach Community College, Institute of New Dimensions (1988-91)
University of Miami Department of Dermatology and Cutaneous Surgery (1987-94)

SOCIETY/MEMBERSHIPS
American Academy of Dermatology – Fellow
American Board of Dermatology – Diplomate
American Society of Dermatologic Surgery – Fellow
Florida Society of Dermatology and Dermatologic Surgery
Florida Society of Dermatologic Surgeons
Palm Beach County Society for Dermatology & Cutaneous Surgery – President (1987-89)
Palm Beach County Medical Society
Cancer Care Committee at Bethesda Memorial Hospital (1989-90)
The “U” Dermatology Association

PUBLICATIONS
1. Gretzula JC, Penneys NS: “Transient Acantholytic Dermatosis: An Immunohistochemical Study.“ Arch Dermatol 1986; 122:972
2. Gretzula JC, Penneys NS: “Complex Viral and Fungal Skin Lesions of Patients with AIDS. “ J Am Acad Dermatol 1987; 16:1151
3. Gretzula JC, Hevia O, Weber PJ: “Blooms Syndrome.” J Am Acad Dermatol 1987; 17:479
4. Gretzula JC, Weber PJ, Garland LD, Hevia O, Menn H: “Syringoid Eccrine Carcinoma.” J Dermatol Surg Oncol 1987;
5. Gretzula JC, Weber PJ, McGregor JM: “Multiple Papules in a Localized Area: A case of Segmental Neurofibromatosis.“ Arch Dermatol 1988; 124:1101.
6. Gretzula JC, Weber PJ, Hevia O, DiLiberti J: “The Ruvalcaba-Myhre-Smith Syndrome.” Pediatr Dermatol 1988; 5:28.
7. Gretzula JC, Weber PJ, Hevia O, Rabinovitz HC: “Primary Mucinous Carcinoma.” J Dermatol Surg Oncol 1988; 14:170.
8. Gretzula JC, Weber PJ, Hevia O, Poulos E: “Malignant Cylindroma.” (Submitted to J Cutan Pathol).
9. Gretzula JC, Weber PJ, Hevia O: “A Synopsis of Dermatopathologic Stains for Clinicians and Residents.” (Submitted to J Milt Derm).
10. Gretzula JC, Weber PJ, Hevia O: “Eccrine Porocarcinoma.” (Submitted to J Dermatol Surg Oncol).
11. Gretzula JC, Weber PJ, Hevia O,Barquin P,Gould EW,Garland LD: “Dermatofibrosarcoma Protuberans.” J Dermatol Surg Oncol 1988; 14:555.
12. Gretzula JC, Weber PJ: “Surgical Dermatology, Advances in Current Practice.” 1st Edn. (Martin Dunitz: London 1993).

INVITED LECTURES:

1. University of Miami, Second Annual Residents Conference., “The Ruvalcaba-Myhre-Smith Syndrome” (June 14, 1986).

2. Dowling Club, Miami Dermatologic Society., “Complex Cutaneous Infections in the AIDS Patient” (December 1, 1986).

3. American Society of Dermatopathology, Annual Seminar Care Conference., “Binary Skin Infections on the Knee of Patients with Aids” (December 4, 1986).

4. University of Miami, Third Annual Residents Conference., “Complex Cutaneous Infections in the AIDS Patient” (June 13, 1987).

5. Palm Beach Scleroderma Society., “Cutaneous Manifestations of Scleroderma” (December 13, 1988).

6. Indian River Pharmacy Association., “Treatment of Male-Pattern Baldness” (January 19, 1989).

7. Palm Beach Regional Hospital, Department of Family Practice., “Hair Loss: Causes, Prevention and Treatment” (February 14, 1989).

8. Palm Beach County School District – Elementary P.E. Teachers., “Sun Appreciation” (January 26, 1990).

9. Neighborhood Forums: Boynton Beach City Library., “Problems of the Aging Skin” (March 21, 1990).

ABSTRACTS:

1. “Binary Skin Infections on the Knee of Patients with AIDS.” – Amer Soc Dermpath (December 1986) with Penneys, NS.